Abstract: Artificial intelligence (AI) is rapidly transforming scientific discovery, enabling breakthroughs in areas ranging from drug discovery to modeling complex physical systems. In the life sciences, AI has traditionally been applied to prediction tasks such as classifying molecules as toxic or non-toxic, estimating drug properties, or solving partial differential equations. These discriminative models have proven powerful, but they are inherently limited to mapping existing inputs to deterministic outputs. A new wave of methods is shifting the paradigm from discrimination to generation: creating new possibilities, such as generating novel molecules or designing new drugs. By reframing AI as both a predictive and generative engine, this shift offers new pathways for accelerating discovery and innovation in life sciences at an unprecedented scale. This talk will cover several aspects of AI for Science (AI4Sci), beginning with advances in discriminative models for molecular systems and solving PDEs, and then turning to generative approaches, including diffusion models for 3D molecular generation and large language models for drug editing. Together, these developments illustrate how moving from prediction to creation is redefining what AI can contribute to science.

Bio: Wenhan Gao is a fourth-year Ph.D. student in Applied Mathematics under the supervision of Professor Yi Liu. He was also a Staff Research Scientist Intern at VISA Research, where he worked on large language models (LLMs) and multi-agent systems for commerce. Wenhan's research focuses on AI for Science (AI4Sci), with a particular emphasis on generative AI. His work looks deep into the fundamental mechanisms of AI models when applied to scientific tasks, and he strives to incorporate established scientific priors, such as symmetry, into model design. He has published papers as a first or corresponding author in leading AI and computational venues, including ICLR, ICML, NeurIPS, TMLR, ACL, and the Journal of Computational Physics. In addition to his research, Wenhan has served as a reviewer and oral session chair for top AI conferences and as a lecturer for both undergraduate and graduate courses at Stony Brook University.

Location: IACS Seminar Room or Zoom

This seminar will take place in person and online*

Join Zoom Meeting: https://stonybrook.zoom.us/j/91670093552?pwd=2EcniXqPZLTpa4ZBKRs1zAjYqs1LS0.1

Meeting ID: 916 7009 3552
Passcode: 434045

Join the Collaborative for the Earth, the Department of Political Science, and the AI Innovation Institute as we welcome Lav Varshney, Ph.D., Della Pietra Infinity Professor and Inaugural Director of the AI Innovation Institute.

The Physical Economy of Intelligence: Marketcraft, Data Centers, and Climate

Artificial intelligence is often described as immaterial, yet it is a rapidly growing physical industry built from memory chips, servers, concrete, land, electricity, water, and capital. This talk develops a marketcraft perspective on AI and climate, treating memory, compute, and intelligence as interdependent goods shaped by supply constraints, demand shocks, long investment cycles, environmental externalities, and the design of markets and institutions. This framing helps explain why sustainable AI cannot be achieved through more efficient algorithms alone: it also requires better lifecycle accounting, procurement standards, flexible computing, and contracts that shift computational activity toward environmentally favorable times and places. The talk will connect these system-level ideas to work on generative design and experimental validation of low-carbon concrete for data-center construction, as well as AI-enabled optimization of wastewater operations that have each reduced energy/carbon by 30 percent or more. Together, these examples show how the co-design of algorithms, physical infrastructure, markets, and public policy can reduce AI's environmental footprint while using AI to accelerate climate solutions.

Date & Time: Wednesday, September 23, 2026 | 12:30 PM - 1:50 PM

Location: Laufer Center

Registration is compulsory

For any questions and accessibility requests or accommodations, please contact Jennifer Gilday at c4e@stonybrook.edu or call 631-632-4625.

Abstract: Visual generation is a fundamental problem in computer vision and graphics, with applications ranging from 3D capture to image and video synthesis. Despite rapid progress in neural rendering and generative models, efficiency remains a key bottleneck: high-quality 3D reconstruction often relies on dense multi-view supervision; high-fidelity 3D synthesis requires costly optimization, training, and rendering; and modern image and video generators require substantial computation as the number of tokens grows rapidly for high-resolution generation. This dissertation focuses on efficient visual generation by improving sample efficiency in 3D reconstruction, representation efficiency in 3D generation, and computational efficiency in image and video synthesis. First, we improve the sample efficiency of neural implicit surface reconstruction. We integrate multi-view stereo probability volumes as a geometric regularizer, enabling high-quality sparse-view reconstruction from as few as three input images. Next, we introduce an explicit 3D representation for 3D generation, built from multi-view depth and RGB images with 3D Gaussian features. This design allows the model to use 2D generative priors while enforcing multi-view consistency through epipolar attention. We then address the computational bottleneck in image and video synthesis with importance-based token merging. Our method uses importance signals available during generation to preserve critical information while merging redundant tokens. Finally, we enable efficient mixed-resolution diffusion transformers via phase-aligned attention. This approach stabilizes attention under mixed-resolution token grids and unlocks high-fidelity image and video generation at reduced cost. Taken together, these contributions reduce the data requirements, representational overhead, and computational demands, thereby providing a foundation for high-quality, scalable, and efficient visual generation.

Speaker: Haoyu Wu

Location: NCS 120

The International Neuroethics Society (INS) Speaker Series on AI & Consciousness

AI has existed as a tool for a long time, performing simple tasks such as sorting documents, suggesting music, and so on. But with the development of new generations of AI, the perception of its value to society has been increasing, as it can bring potential and promising benefits in many areas of human life. AI is known to have errors or biases that result in strange or even dangerous responses, but what happens when in AI-human interaction, the latter have errors or biases? cultural errors or biases? And what could be the implications for human relationships?

Speaker Bio

Dr. Karen Herrera-Ferrá is an independent and global consultant on ethical, medical, psychological, legal, social, cultural, policy-making, human rights and political issues and concerns on the development and use of neuroscience, neurotechnology and AI. She is a former member of the Board of Directors of the International Neuroethics Society.

Register here

https://umaryland.zoom.us/meeting/register/tJMvfuqsqDspG9BKMLfUU49UbuUyP_IEvXRh


Reception to follow.

Abstract:
In this talk, I will present our journey of developing diverse, adaptive, uncertainty-calibrated AI planning agents that can robustly communicate and collaborate for multi-agent reasoning (on math, commonsense, coding, etc.) as well as for interpretable, controllable multimodal generation (across text, images, videos, audio, layouts, etc.). In the first part, we will discuss improving reasoning via multi-agent discussion among diverse LLMs and structured distillation of these discussion graphs (ReConcile, MAGDi), adaptively learning to balance abstraction, decomposition, refinement, and fast+slow thinking in LLM-agent reasoning (ReGAL, ADaPT, MAgICoRe, System-1.x), as well as confidence calibration in LLMs via speaker-listener pragmatic reasoning and making LLMs better teammates via multi-agent positive-negative persuasion balancing (LACIE, PBT). In the second part, we will discuss interpretable and control-lable multimodal generation via LLM-agents based planning and programming, such as layout-controllable image generation (and evaluation) via visual programming (VPGen+VPEval), consistent multi-scene video generation via LLM-guided planning (VideoDirectorGPT), interactive and composable any-to-any multimodal generation (CoDi, CoDi-2), as well as feedback-driven multi-agent interaction for adaptive environment/data generation via weakness discovery (EnvGen, DataEnvGym).
Bio:
Dr. Mohit Bansal is the John R. & Louise S. Parker Distinguished Professor and the Director of the MURGe-Lab (UNC-NLP Group) in the Computer Science department at UNC Chapel Hill. He received his PhD from UC Berkeley in 2013 and his BTech from IIT Kanpur in 2008. His research expertise is in natural language processing and multimodal machine learning, with a particular focus on multimodal generative models, grounded and embodied semantics, faithful language generation, and interpretable, efficient, and generalizable deep learning.
Abstract:
Coarse grained (CG) models alleviate the drawbacks of all-atom simulations. The latter still pose challenges because they are computationally expensive and give access to limited spatiotemporal scales, despite the use of modern high-performance computing clusters. CG models ignore some of the atomistic degrees of freedom, leading to fewer interatomic interactions, hence less computing time. Introducing such models emphasizes the need to properly manage these multiple scales, by carefully deriving potentials and reconstructing conformations from their CG representations, usually with the help of Machine Learning. Following a bottom-up and force matching approach, we train a Physics-Informed Neural Network to extract the CG force field parameters from all-atom simulation data. We verify our approach by applying it to fibrin monomers to study multiple-fibrin polymerization in solution at the microsecond scale, after modifying the force field to incorporate further non-bonded interactions, not present in the training data. Access to these scales will allow us to study the effects of some of the molecules' components. Furthermore, we modify recent solutions in data-driven protein backmapping. Taking advantage of the developments in graph neural networks and variational inference, we introduce an intermediate step in the all-atom reconstruction of a molecule given its CG configuration, in an attempt to more accurately de-coarsen structures whose atom-to-CG-beads ratio is very high. The combined effect of our new forward and inverse coarse graining methodology will enable the in silico study of many phenomena that are highly dynamic and intrinsically multiscale.

Bio:
Georgios Kementzidis is a third year PhD student in the Department of Applied Mathematics and Statistics at Stony Brook University. His advisor is Dr. Yuefan Deng. His research interests lie at the intersection of Computational Science, molecular dynamics (MD) simulations, and Machine Learning (ML) applications to Computational Biophysics. He is particularly interested in coarse-graining and multi-scale simulations.

*Note: this seminar will be held in-person (food provided on a first-come, first serve basis) and online*

Join Zoom Meeting https://stonybrook.zoom.us/j/99510099036?pwd=EyowuLBGvUVLZDBlG6F6chkMICFOZ7.1
Meeting ID: 995 1009 9036
Passcode: 132419
Abstract: Robot control has evolved from optimization-based controllers---precise but task-specific---through deep reinforcement learning's learned policies, to Vision-Language-Action (VLA) models that leverage pretrained vision-language backbones for language-conditioned manipulation across diverse tasks.
Despite their promise, VLAs exhibit a critical limitation: they function primarily as trajectory learners rather than skill learners. Recent evaluations reveal that VLAs often fail when faced with even minor variations in object initialization or environmental conditions, suggesting they memorize specific trajectories rather than acquiring generalizable manipulation skills. Attempts to address this through 3D spatial representations have shown limited success, indicating that the missing component may be more fundamental than geometric understanding alone.
This work argues that World Models (WMs)---internal representations that predict future states given actions---constitute the missing piece for robust VLA systems. We present one completed contribution and two ongoing investigations.
We developed a dual-layer world model for human-robot interaction that anticipates both physical scene evolution and latent human preferences for assistive tasks. Building on these foundations, we present ongoing work probing VLA internal representations to verify implicit world model existence, and propose a WM-VLA integration approach operating in the native visual domain through embedding prediction and image decoding.
Together, these contributions and investigations establish a foundation for WM-VLA systems, pointing toward robust, generalizable robot policies.
Speaker: Jason Qin
Location: NCS 220
Objectives:
1. Explain the clinical radiology workflow, and highlight how AI is currently in use to impact each step
2. Describe how radiologists interact with the currently available tools, highlighting both positive andnegative examples
3. Offer a brief description of how these tools are approved, validated, and reimbursed
4. Explore the utility of cutting edge AI techniques in diagnostic radiology

Speaker:
Dr. David Payne, MD Neuroradiologist and Assistant Professor, Rush University Medical Centre

Remote Access:
Zoom: https://stonybrook.zoom.us/j/95617197636?pwd=KytzZ2pVRG9SZGpKZUtpNXJISjNjZz09
Meeting ID: 95617197636
Passcode: 924293

When: Thu: 10/28/2021, 10 am
Where: NCS Room 220, or
Zoom: https://stonybrook.zoom.us/j/97978463739?pwd=aVJFVERQa25jYjJrOFZEcWVuSzJLdz09

Deep Surface MeshesPascal FuaEPFLGeometric Deep Learning has recently made striking progress with the advent of Deep Implicit Fields (SDFs). They allow for detailed modeling of watertight surfaces of arbitrary topology while not relying on a 3D Euclidean grid, resulting in a learnable 3D surface parameterization that is not limited in resolution. Unfortunately, they have not yet reached their full potential for applications that require an explicit surface representation in terms of vertices and facets because converting the SDF to such a 3D mesh representation requires a marching-cube algorithm, whose output cannot be easily differentiated with respect to the SDF parameters. In this talk, I will discuss our approach to overcoming this limitation and implementing convolutional neural nets that output complex 3D surface meshes while remaining fully-differentiable and end-to-end trainable. I will also present applications to single view reconstruction, physically-driven Shape optimization, and bio-medical image segmentation.


Bio:
Pascal Fua received an engineering degree from Ecole Polytechnique, Paris, in 1984 and a Ph.D. in Computer Science from the University of Orsay in 1989. He joined EPFL (Swiss Federal Institute of Technology) in 1996 where he is a Professor in the School of Computer and Communication Science and head of the Computer Vision Lab. Before that, he worked at SRI International and at INRIA Sophia-Antipolis as a Computer Scientist. His research interests include shape modeling and motion recovery from images, analysis of microscopy images, and Augmented Reality. He has (co)authored over 300 publications in refereed journals and conferences. He has received several ERC grants. He is an IEEE Fellow and has been an Associate Editor of IEEE journal Transactions for Pattern Analysis and Machine Intelligence. He often serves as program committee member, area chair, and program chair of major vision conferences and has cofounded three spinoff companies.

Abstract:
Quantum Machine Learning (QML) holds significant promise for solving computational challenges across diverse domains. However, its practical deployment is constrained by the limitations of noisy intermediate-scale quantum (NISQ) devices, including noise, limited scalability, and trainability issues in variational quantum circuits (VQCs). We introduce the multi-chip ensemble VQC framework, which partitions high-dimensional computations across smaller quantum chips to enhance scalability, trainability, and noise resilience. We show that this approach mitigates barren plateaus, reduces quantum error bias and variance, and maintains robust generalization through controlled entanglement. Designed to align with current and emerging quantum hardware, the framework demonstrates strong potential for enabling scalable QML on near-term devices, as validated by experiments on standard benchmark datasets (MNIST, FashionMNIST, CIFAR-10).

IACS Student Seminar Speaker:
Junghoon Park, Seoul National University
BA in Economics, Seoul National University, Korea
PhD Candidate for Interdisciplinary Programme in Artificial Intelligence at Seoul National University
Visiting Researcher at Brookhaven National Laboratory


Current Research Interests
Quantum Machine Learning


Recent Papers
Park, J., Cha, J., Chen, S. Y.-C., Yoo, S., & Tseng, H.-H. (2025). Addressing the Current Challenges of Quantum Machine Learning through Multi-Chip Ensembles. In Review at ICML.
Park, J., Kim, K., & Cha, J. (2025). How to Assess AI Ethics: Suggestions for Ethical Rating Agencies. In Review at IJCAI.
Park, J., Cha, J., Chen, S. Y.-C., Yoo, S., & Tseng, H.-H. (2024, 15-20 Sept.). Over the Quantum Rainbow: Explaining Hybrid Quantum Reinforcement Learning. 2024 IEEE International Conference on Quantum Computing and Engineering (QCE).
Park, J., Lee, E., Cho, G., Hwang, H., Kim, B.-G., Kim, G., Joo, Y. Y., & Cha, J. (2024). Gene-Environment Pathways to Cognitive Intelligence and Psychotic-Like Experiences in Children. eLife, 12, RP88117. DOI:10.7554/eLife.88117

This seminar will be held in person (food provided!) in the IACS Seminar Room, and online (zoom link below!)
https://stonybrook.zoom.us/j/96548538719?pwd=jBmI43H68q2UkdcRRjVbTkgrC6F942.1
Meeting ID: 965 4853 8719
Passcode: 493290